Slow Cooker Pork Tenderloin delivers tender, juicy results with minimal effort. This easy recipe uses a simple spice rub and flavorful sauce, perfect for busy weeknights or meal prep. Cook it low and slow to 145°F for the best texture every time.

Pork Tenderloin vs Pork Loin
Pork tenderloin and pork loin come from different parts of the pig, so they cook differently. Tenderloin is long, thin, and very lean at about 1 pound each, while pork loin forms a thicker roast around 3-4 pounds with more fat.
| Feature | Pork Tenderloin | Pork Loin |
|---|---|---|
| Shape/Size | Long, thin (1 lb each) | Thick roast (3-4 lbs) |
| Fat Content | Very lean | Often has fat cap |
| Cook Time | 2-3 hours on low | 6-8 hours on low |
| Best For | Quick slow cooking | Longer braises |
Always use tenderloin for this recipe to avoid dry results.
Ingredients
This recipe serves 6-8 using two 1-pound tenderloins. Scale as needed.
For the Pork and Rub:
- 2 pounds pork tenderloin (about two 1-pound pieces)
- 2 teaspoons garlic powder
- 2 teaspoons chili powder
- 1 teaspoon smoked paprika
- 1 teaspoon onion powder
- 1 teaspoon dried parsley (or Italian seasoning)
- 1 teaspoon kosher salt
- 1/2 teaspoon black pepper
For the Sauce (Choose One Variation):
- BBQ Style: 2 cups barbecue sauce, 1 tablespoon Dijon mustard
- Honey Balsamic Glaze: 1/2 cup low-sodium chicken broth, 3 tablespoons balsamic vinegar, 2 tablespoons honey, 1 tablespoon ketchup, 2 teaspoons cornstarch
- Gravy Style: 1/2 cup low-sodium beef broth, 1 packet pork gravy mix (or au jus), 4 tablespoons salted butter (sliced)
Optional Add-Ins:
- 1 medium onion, thinly sliced (for base flavor)
- Chopped fresh parsley, for garnish
Nutrition (Per Serving, BBQ Variation, Approx.):
Calories: 280 | Protein: 32g | Carbs: 18g | Fat: 8g | Sodium: 650mg (varies by brands).
Step-by-Step Instructions
Prep takes 5 minutes. A 6-quart slow cooker works best.
- Trim and Season: Pat tenderloins dry. Mix rub ingredients in a bowl. Coat all sides generously. (Trim silver skin if present for tenderness.)
- Prep Cooker: Spray slow cooker with oil. Add sliced onions if using.
- Optional Sear: For extra flavor, heat 2 tablespoons oil in a skillet over medium-high. Sear each tenderloin 2 minutes per side until golden. Skip for no-fuss prep.
- Add Sauce: Place pork in cooker. Pour chosen sauce over top. For glaze, whisk liquids first. For gravy, sprinkle mix and dot with butter.
- Cook: Cover and cook on low 2-3 hours or high 1.5-2 hours. Check at 2 hours on low.
- Check Doneness: Use an instant-read thermometer in the thickest part. Remove at 145°F (it rises to 150-155°F while resting). Rest 5-10 minutes tented with foil, then slice into medallions.
- Thicken Sauce (Optional): Strain juices into a pot. Simmer with 1 teaspoon cornstarch + 1 teaspoon water slurry until thickened, 2-3 minutes.
Serve sliced pork with sauce spooned over top. Garnish with parsley.
Recipe Variations
Mix up flavors without changing cook time much.
| Variation | Key Ingredients | Flavor Profile |
|---|---|---|
| BBQ Style | BBQ sauce + Dijon + chili powder | Sweet-smoky |
| Honey Glaze | Balsamic + honey + cornstarch | Tangy-sweet |
| Gravy Style | Beef broth + gravy mix + butter | Savory-rich |
| Herb Garlic | Broth + extra garlic + rosemary | Fresh-aromatic |
All hit 145°F in 2-3 hours low.
Cooking Times and Temperature Guide
Pork tenderloin cooks fast in a slow cooker due to its leanness. Always verify with a thermometer.
- Low Setting: 2-3 hours (best for juicy results)
- High Setting: 1.5-2 hours
- Safe Internal Temp: 145°F (medium-rare pink is safe and tender). Resting adds 5-10°F.
- Tips: Larger tenderloins take longer. Test early to avoid drying out. Slow cookers vary, so start checking at minimum time.
Serving Suggestions
Pair with creamy sides to soak up sauce.
- Starches: Mashed potatoes, rice, baked potatoes, or crusty bread.
- Veggies: Green beans, roasted broccoli, sauteed kale, or corn on the cob.
- Full Meals:
- BBQ style over mashed potatoes with fried apples.
- Gravy style with green beans and cornbread.
- Glaze with rice and Air fryer asparagus.
Serves 6-8 generously.
Storage and Reheating
Leftovers stay juicy if handled right.
- Fridge: Airtight container up to 4 days.
- Freezer: Cool completely, then freeze slices in bags up to 3 months.
- Reheat: Low stovetop with sauce, or microwave 30 seconds at a time (covered). Avoid overcooking.
Common Questions
How long does pork tenderloin take in a slow cooker?
2-3 hours on low to reach 145°F.
Can I add vegetables?
Yes! Quick-cooking ones like green beans or peppers after 1.5 hours. Avoid potatoes unless pre-boiled.
Should I sear first?
Optional for flavor, but not needed. Direct to cooker saves time.
What if I have pork loin instead?
Cook 6-8 hours on low. It’s tougher, so slice thin.
Can I make this with one tenderloin?
Yes, halve ingredients (keep broth). Check 30 minutes early.
Is pink pork safe?
Yes at 145°F per USDA guidelines.
More Easy Pork Recipes
Try these next: Crock Pot Pulled Pork, Honey Garlic Pork Chops, or Baked Pork Tenderloin.
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PrintEasy Slow Cooker Pork Tenderloin Recipe
Tender, juicy slow cooker pork tenderloin takes just minutes to prep and delivers incredible flavor with a simple spice rub and rich gravy. This easy crock pot recipe ensures perfect results every time, reaching the safe 145°F internal temperature without drying out.
- Prep Time: PT5M
- Cook Time: PT150M
- Total Time: PT160M
- Yield: 6 1x
- Category: [‘Dinner’,’Main Course’]
- Method: [‘Slow Cooker’]
- Cuisine: [‘American’]
Ingredients
2 pork tenderloins (about 1 pound each)
1 tablespoon olive oil (for optional searing)
1 large onion, thinly sliced
1 cup low-sodium beef broth
4 tablespoons salted butter, cut into pats
2 tablespoons brown sugar
1 teaspoon garlic powder
1 teaspoon smoked paprika
1 teaspoon onion powder
1 teaspoon chili powder
1 teaspoon dried Italian seasoning or thyme
1 teaspoon kosher salt
1/2 teaspoon black pepper
Optional gravy thickener: 1 tablespoon cornstarch + 1 tablespoon water
Instructions
1. Prep the pork: Pat tenderloins dry with paper towels. Trim silver skin (tough membrane) with a sharp knife for tenderness. Mix brown sugar, garlic powder, smoked paprika, onion powder, chili powder, Italian seasoning, salt, and pepper in a bowl. Rub evenly over all sides.
2. Layer the slow cooker: Add sliced onions to the bottom of a 6-quart slow cooker. This creates a flavorful base. Place rubbed tenderloins on top.
3. Optional sear for flavor: Heat olive oil in a skillet over medium-high. Sear each tenderloin 1-2 minutes per side until golden. Transfer to slow cooker. Skip for truly hands-off prep.
4. Add liquids and cook: Pour beef broth around the pork. Top with butter pats. Cover and cook on low for 2-2.5 hours or high for 1.5-2 hours. Check internal temperature with a meat thermometer – remove at 145°F for juicy results. Rest 10 minutes tented with foil.
5. Make gravy: Strain juices into a saucepan. Whisk cornstarch slurry into juices; simmer until thickened, 2-3 minutes. Slice pork and serve with gravy.
Notes
Pro tip: Slow cookers vary, so test early to avoid overcooking. Your kitchen will smell amazing!
Use an instant-read thermometer every time – pork is safe and pink at 145°F after resting.
For low-carb, skip sugar in rub and pair with zucchini noodles.
Add quick-cook veggies like green beans in the last 30 minutes; avoid potatoes unless pre-boiled.
Resting redistributes juices for sliceable tenderness.
Double the rub for bolder flavor or add 1/2 teaspoon cumin for smokiness.
Freezer prep: Rub pork, bag with onions/broth, thaw overnight before cooking.
Nutrition
- Serving Size: 4oz slice
- Calories: 320
- Sugar: 5g
- Sodium: 450mg
- Fat: 12g
- Saturated Fat: 6g
- Unsaturated Fat: 5g
- Trans Fat: 0g
- Carbohydrates: 5g
- Fiber: 0g
- Protein: 40g
- Cholesterol: 120mg
